Multifunctional mesoporous silica nanoparticles for biomedical applications

B Xu, S Li, R Shi, H Liu - Signal transduction and targeted therapy, 2023‏ - nature.com
Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of
nanotechnology applied in the biomedical field, due to their easily tunable structure and …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021‏ - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

The copper age in cancer treatment: from copper metabolism to cuproptosis

W **e, Z Guo, L Zhao, Y Wei - Progress in Materials Science, 2023‏ - Elsevier
Because of their intrinsic physiochemical and biological properties together with essential
role in living organism, copper (Cu) and Cu-based nanomaterials have garnered …

All-in-one theranostic nanoagent with enhanced reactive oxygen species generation and modulating tumor microenvironment ability for effective tumor eradication

Y Liu, W Zhen, L **, S Zhang, G Sun, T Zhang, X Xu… - ACS …, 2018‏ - ACS Publications
Despite regulation of the reactive oxygen species (ROS) level is an intelligent strategy for
cancer therapy, the therapeutic effects of ROS-mediated therapy (including photodynamic …

Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017‏ - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

Compound copper chalcogenide nanocrystals

C Coughlan, M Ibanez, O Dobrozhan, A Singh… - Chemical …, 2017‏ - ACS Publications
This review captures the synthesis, assembly, properties, and applications of copper
chalcogenide NCs, which have achieved significant research interest in the last decade due …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018‏ - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020‏ - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

A Smart Nanoreactor Based on an O2-Economized Dual Energy Inhibition Strategy Armed with Dual Multi-stimuli-Responsive “Doorkeepers” for Enhanced CDT/PTT …

S Qiu, X Wu, Z Li, X Xu, J Wang, Y Du, W Pan… - ACS …, 2022‏ - ACS Publications
Activated fibroblast-like synovial (FLS) cells are regarded as an important target for
rheumatoid arthritis (RA) treatment via starvation therapy mediated by glucose oxidase …

The coppery age: copper (Cu)‐involved nanotheranostics

C Dong, W Feng, W Xu, L Yu, H **ang… - Advanced …, 2020‏ - Wiley Online Library
As an essential trace element in the human body, transitional metal copper (Cu) ions are the
bioactive components within the body featuring dedicated biological effects such as …