[HTML][HTML] Spinal cord repair: from cells and tissue engineering to extracellular vesicles

S Guo, I Redenski, S Levenberg - Cells, 2021 - mdpi.com
Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …

Emerging extracellular vesicle-based carriers for glioblastoma diagnosis and therapy

J Wang, Y Liu, F Liu, S Gan, S Roy, I Hasan, B Zhang… - Nanoscale, 2023 - pubs.rsc.org
Glioblastoma (GBM) treatment is still a big clinical challenge because of its highly malignant,
invasive, and lethal characteristics. After treatment with the conventional therapeutic …

Stimulating extracellular vesicles production from engineered tissues by mechanical forces

S Guo, L Debbi, B Zohar, R Samuel, RS Arzi… - Nano Letters, 2021 - ACS Publications
Extracellular vesicles (EVs) have emerged as a promising strategy to promote tissue
regeneration. However, overcoming the low EV production yield remains a big challenge in …

Intravenous administration of mesenchymal stem cell-derived exosome alleviates spinal cord injury by regulating neutrophil extracellular trap formation through …

Y Morishima, M Kawabori, K Yamazaki… - International Journal of …, 2024 - mdpi.com
Spinal cord injury (SCI) leads to devastating sequelae, demanding effective treatments.
Recent advancements have unveiled the role of neutrophil extracellular traps (NETs) …

Advances in extracellular vesicle-based combination therapies for spinal cord injury

T Wang, G Huang, Z Yi, S Dai… - Neural regeneration …, 2024 - journals.lww.com
Spinal cord injury is a severe insult to the central nervous system that causes persisting
neurological deficits. The currently available treatments involve surgical, medical, and …

[HTML][HTML] Exploration for sorting serum exosome as a measure of spinal cord injury severity

Y Li, C Guo, Q Huang, N Zhou, J Wang, Y Huang… - Journal of Radiation …, 2024 - Elsevier
This study aimed to extract exosomes from the serum of rats with spinal cord injury and
explore their potential as indicators for assessing the severity of spinal cord injury. Control …

Extracellular Vesicle Imaging in Theranostic Applications

K Zhang, H Li, K Cheng - Extracellular Vesicle: Biology and Translational …, 2024 - Springer
Extracellular vesicles (EVs) are lipid bilayer vesicles with a diameter ranging from 30 to 150
nm, playing a crucial role in mediating cell-to-cell communication under both physiological …