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Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer
H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …
Application of exosomes as liquid biopsy in clinical diagnosis
B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum
K Brennan, K Martin, SP FitzGerald, J O'sullivan… - Scientific reports, 2020 - nature.com
Extracellular vesicles (EVs) are nano-sized vesicles containing nucleic acid and protein
cargo that are released from a multitude of cell types and have gained significant interest as …
cargo that are released from a multitude of cell types and have gained significant interest as …
Isolation and characterization of exosomes for cancer research
L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …
Extracellular vesicles in liquid biopsies as biomarkers for solid tumors
B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …
exponentially, demonstrating the great potential of screening body fluids for diagnosis …
Liquid biopsies, novel approaches and future directions
A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Recent progress in exosome research: isolation, characterization and clinical applications
X Wang, J **a, L Yang, J Dai, L He - Cancer Gene Therapy, 2023 - nature.com
Exosomes, a kind of nano-vesicles released by various cell types, carry a variety of “cargos”
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
Diagnostic potential of exosomal extracellular vesicles in oncology
M Andre, A Caobi, JS Miles, A Vashist, MA Ruiz… - BMC cancer, 2024 - Springer
Liquid biopsy can detect circulating cancer cells or tumor cell-derived DNA at various stages
of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as …
of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as …