Biosystem‐inspired engineering of nanozymes for biomedical applications
L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
Synergistic effects between metal nanoparticles and commercial antimicrobial agents: A review
Nanotechnology has expanded into a broad range of clinical applications. In particular,
metal nanoparticles (MNPs) display unique antimicrobial properties, a fundamental function …
metal nanoparticles (MNPs) display unique antimicrobial properties, a fundamental function …
Oral antiviral treatments for COVID-19: opportunities and challenges
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication
and prevent disease progression to a more severe form. However, the timing of antiviral …
and prevent disease progression to a more severe form. However, the timing of antiviral …
Synthesis, molecular features and biological activities of modified plant polysaccharides
S Mukherjee, S Jana, S Khawas, J Kicuntod… - Carbohydrate …, 2022 - Elsevier
Plant polysaccharides represent a natural source material characterized by high ubiquity,
abundance and biological activities that can be utilised as organic matter in numerous …
abundance and biological activities that can be utilised as organic matter in numerous …
Recent applications of vinyl sulfone motif in drug design and discovery
Vinyl sulfone with electrophilic character is not only a versatile building block for various
organic transformations but also is a key structural unit in a large number of biologically …
organic transformations but also is a key structural unit in a large number of biologically …
Nanozybiotics: advancing antimicrobial strategies through biomimetic mechanisms
C Zhou, Q Wang, H Cao, J Jiang, L Gao - Advanced Materials, 2024 - Wiley Online Library
Infectious diseases caused by bacterial, viral, and fungal pathogens present significant
global health challenges. The rapid emergence of antimicrobial resistance exacerbates this …
global health challenges. The rapid emergence of antimicrobial resistance exacerbates this …
The 1, 2, 3-triazole 'all-in-one'ring system in drug discovery: A good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool
ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
chemistry due to its unique structural properties, synthetic versatility and pharmacological …
4′-Modified nucleosides for antiviral drug discovery: achievements and perspectives
J Chang - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Modified nucleosides show therapeutic promise for antiviral therapies.
However, issues including the emergence of drug resistance, toxicity, and coinfections have …
However, issues including the emergence of drug resistance, toxicity, and coinfections have …
Structural, electronic, and electrostatic determinants for inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease
Creating small-molecule antivirals specific for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins is crucial to battle coronavirus disease 2019 (COVID …
coronavirus 2 (SARS-CoV-2) proteins is crucial to battle coronavirus disease 2019 (COVID …
Catalytic antimicrobial therapy using nanozymes
Q Wang, J Jiang, L Gao - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Nanozymes are nanomaterials with enzyme‐like characteristics, which catalyze the
conversion of enzyme substrates and follow enzymatic kinetics under physiological …
conversion of enzyme substrates and follow enzymatic kinetics under physiological …