The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

The number and types of venom components that affect ion-channel function are reviewed.
These are the most important venom components responsible for human intoxication …

Scorpion venoms consist of a complex of several toxins that exhibit a wide range of
biological properties and actions, as well as chemical compositions, toxicity, and …

Much of our knowledge on K+-channels was elucidated using specific peptide ligands
isolated from a number of venomous organisms. Recently, this field received a strong …

Scorpions are among the oldest terrestrial arthropods, which are distributed worldwide,
except for Antarctica and some Pacific islands. Scorpion envenomation represents a public …

Voltage-gated potassium channels play a key role in human physiology and pathology.
Reflecting their importance, numerous channelopathies have been characterised that arise …

Potassium (K+) channels are a widespread superfamily of integral membrane proteins that
mediate selective transport of K+ ions through the cell membrane. They have been found in …

Tityus serrulatus is considered the most dangerous scorpion in South America and
responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion …

K+ channels are macromolecules embedded in biological membranes, where they play a
key role in cellular excitability and signal transduction pathways. Knowledge of their …

Of the 14 extant scorpion families, Buthidae has the most thoroughly characterized venoms.
Most of this characterization, however, has been limited to species with medically significant …