The role of resveratrol in cancer therapy

JH Ko, G Sethi, JY Um, MK Shanmugam… - International journal of …, 2017 - mdpi.com
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling …

SA Almatroodi, MA Alsahli, A Almatroudi, AK Verma… - Molecules, 2021 - mdpi.com
Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

Targeting inflammation in cancer prevention and therapy

J Todoric, L Antonucci, M Karin - Cancer Prevention Research, 2016 - aacrjournals.org
Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …

[HTML][HTML] Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

[HTML][HTML] Synergistic effects of plant derivatives and conventional chemotherapeutic agents: an update on the cancer perspective

R Pezzani, B Salehi, S Vitalini, M Iriti, FA Zuñiga… - Medicina, 2019 - mdpi.com
Synergy is a process in which some substances cooperate to reach a combined effect that is
greater than the sum of their separate effects. It can be considered a natural “straight” …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

[HTML][HTML] Unveiling the potential effects of resveratrol in lung cancer treatment: Mechanisms and nanoparticle-based drug delivery strategies

B Najafiyan, ZB Hosseini, S Esmaelian… - Biomedicine & …, 2024 - Elsevier
Lung cancer ranks among the most prevalent forms of cancer and remains a significant
factor in cancer-related mortality across the world. It poses significant challenges to …

Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Role of STAT3 in cancer metastasis and translational advances

MZ Kamran, P Patil, RP Gude - BioMed research international, 2013 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic
transcription factor, originally discovered as a transducer of signal from cell surface …

Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

J Tomé-Carneiro, M Larrosa… - Current …, 2013 - benthamdirect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …