Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Inflammation is associated with the development and malignant progression of most
cancers. As most of the cell types involved in cancer-associated inflammation are genetically …

Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic
transcription factor, originally discovered as a transducer of signal from cell surface …

Synergy is a process in which some substances cooperate to reach a combined effect that is
greater than the sum of their separate effects. It can be considered a natural “straight” …

Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …

Chronic infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and high-
calorie diet have been recognized as major risk factors for the most common types of cancer …