Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

Spirooxindoles are privileged scaffolds in diverse bioactive natural products and
pharmaceuticals, significant achievements for the construction of these molecules have thus …

A swift and green one-pot method was improved for the preparation of new pyranopyrazole
analogues using iron-doped heteropoly acid [(Fe 5 (PW 10 V 2 O 40) 3](FePWV) as an …

Herein, one-pot synthesis of (E)-5-bromo-3-(phenylimino) indolin-2-one (5BPI molecule),
density function theory for validation of the synthesized molecule, and biological activities …

Two novel β-enaminonitrile derivatives 5a, b bearing pyrano [2, 3-c] pyrazole moiety were
synthesized using Multi Component Reaction (MCR) technique by reacting the ethyl …

In this review, we describe a collection and assessment of 16 anticancer drugs approved by
the US FDA between 2021 to June 2022, which include small and big amide group …

Abstract The published molecule (S)-3-Benzyl-5-(phenylselanyl)-6-(p-tolyl)-3, 4-
dihydropyran-2-one (3B6PL) was selected for the identification of anticancer properties, and …

Spirooxindoles represent a special scaffold for pharmaceuticals and natural products, and
significant advancements have been achieved in their synthesis in recent years. Among …

A series of alkynylated pyrrole derivatives were meticulously designed, drawing inspiration
from the structure of 3‐alkynylpyrrole‐2, 4‐dicarboxylates, which were synthesized via a …

Herein, click chemistry was chosen to synthesize 2AIPC using Knoevenegel and Michael
addition reactions. In this synthesis, Lewis base was attracted by the generation of sp 3 …