Immunological and metabolic causes of infertility in polycystic ovary syndrome

AM Kicińska, RB Maksym, MA Zabielska-Kaczorowska… - Biomedicines, 2023 - mdpi.com
Infertility has been recognized as a civilizational disease. One of the most common causes
of infertility is polycystic ovary syndrome (PCOS). Closely interrelated immunometabolic …

Mechanisms affecting brain remodeling in depression: do all roads lead to impaired fibrinolysis?

S Hoirisch-Clapauch - Molecular Psychiatry, 2022 - nature.com
Fibrinolysis occurs when plasminogen activators, such as tissue plasminogen activator
(tPA), convert plasminogen to plasmin, which dissolves the fibrin clot. The proteolytic activity …

The extracellular vesicles proteome of endometrial cells simulating the receptive menstrual phase differs from that of endometrial cells simulating the non-receptive …

AR Hart, NLA Khan, K Dissanayake, K Godakumara… - Biomolecules, 2023 - mdpi.com
Successful embryo implantation into a receptive endometrium requires mutual endometrial-
embryo communication. Recently, the function of extracellular vehicles (EVs) in cell-to-cell …

From blood to brain: Exploring the role of fibrinogen in the pathophysiology of depression and other neurological disorders

S Patel, V Govindarajan, S Chakravarty… - International …, 2024 - Elsevier
Recent findings indicate that fibrinogen, a protein involved in blood clotting, plays a
significant role in neuroinflammation and mood disorders. Elevated fibrinogen levels are …

The fibrinolytic system in peripartum depression

S Hoirisch-Clapauch - Seminars in thrombosis and hemostasis, 2023 - thieme-connect.com
The relationship between depression and reduced fibrinolytic activity reflects the role of
tissue plasminogen activator and plasmin in brain remodeling underlying resilience …

A strong Association between Plasminogen Activator Inhibitor Type-1 (-657 4G/5G PAI-1) and the Development of Pre-eclampsia

OY El-Khawaga, H Ahmed, A ElSaid, H Shalaby - 2023 - researchsquare.com
Abstract Introduction: Pre-eclampsia (P-EC) is a multisystem disorder of pregnancy,
characterized by new-onset hypertension and proteinuria. Deregulation of the coagulation …

[CITAT][C] A new journal in a brave new world

LA Norris, ES Papadakis - Thrombosis Update, 2020 - Elsevier