Recent advances in Schiff base metal complexes derived from 4-aminoantipyrine derivatives and their potential applications

A Sakthivel, K Jeyasubramanian, B Thangagiri… - Journal of Molecular …, 2020 - Elsevier
In this review, the importance of 4-aminoantipyrine (4-AAP) and its derivatives after forming
a Schiff base by condensing with different kinds of carbonyl compounds and their metal …

Pyrazolopyridine: An efficient pharmacophore in recent drug design and development

D Atukuri - Chemical Biology & Drug Design, 2022 - Wiley Online Library
Among the various heterocyclic molecules employed for drug design and discovery,
pyrazolopyridine is one of the promising pharmacophores. Pyrazolopyridine is a result of …

Anti-covid-19 drug analogues: synthesis of novel pyrimidine thioglycosides as antiviral agents against SARS-COV-2 and avian influenza H5N1 viruses

MA Abu-Zaied, GH Elgemeie, NM Mahmoud - ACS omega, 2021 - ACS Publications
A class of pyrimidine thioglycoside analogs (6a–h) were synthesized from a reaction of 2-
cyano-3, 3-dimercapto-N-arylacrylamide (2a–d) and thiourea to produce the corresponding …

Efficient synthesis and docking studies of novel benzothiazole-based pyrimidinesulfonamide scaffolds as new antiviral agents and Hsp90α inhibitors

RA Azzam, RR Osman, GH Elgemeie - ACS omega, 2020 - ACS Publications
A series of novel substituted 2-pyrimidylbenzothiazoles incorporating either sulfonamide
moieties or the amino group at C2 of the pyrimidine ring were synthesized and evaluated for …

Dinuclear Zn (II) complexes with Schiff base ligands derived from 4-aminoantipyrine; crystal structure and catalytic activity in the synthesis of tetrazoles

R Bikas, MH Rashvand, N Heydari… - Journal of Molecular …, 2023 - Elsevier
Two new phenolato bridged dinucelar Zn (II) complexes,[Zn 2 (L 1) 2 (N 3) 2](1) and [Zn 2 (L
2) 2 (N 3) 2](2), were synthesized where HL 1 and HL 2 are tridentate Schiff base ligands …

Experimental and theoretical investigation into the design of nickel (II), copper (II), and zinc (II) complexes substituted with pyrazole ligand

MK Alenzi, M Azam, SI Al-Resayes, S Kansız… - Polyhedron, 2024 - Elsevier
A novel series of metal complexes of 3d elements of the type,[MLCl 2][M= Ni (II), Cu (II) & Zn
(II), L= ligand] produced from an ampyrone-based ligand was discussed. A thorough …

Colorimetric Determination of phenylephrine hydrochloride drug Using 4-Aminoantipyrine: Stability and higher sensitivity

AM Aljeboree, AN Alshirifi - Journal of Pharmaceutical …, 2018 - search.proquest.com
Among these methods, adsorption is the simplest, cheapest, and most versatile technique
for holding these pollutants [14], Activated carbon [15, 16], biochar [17], mesoporous silica …

Supramolecular architecture, thermal, quantum chemical analysis and in vitro biological properties on sulfate salt of 4-aminoantipyrine

AC Devi, V Siva, S Thangarasu, S Athimoolam… - Journal of Molecular …, 2021 - Elsevier
A new hydrogen-bonded single crystals of 4-aminoantipyrinium bisulfate monohydrate
(4AAPS) have been grown by conventional solution growth technique. The grown crystal …

Synthesis of novel pyridine and pyrimidine thioglycoside phosphoramidates for the treatment of COVID-19 and influenza A viruses

MA Abu-Zaied, GH Elgemeie… - … Nucleotides & Nucleic …, 2022 - Taylor & Francis
A novel series of pyridine, cytosine, and uracil thioglycoside analogs (4a–i, 9a, b, and 13a,
b, respectively) and their corresponding phosphoramidates (6a–I, 10a, b, and 14a, b …

Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a] pyrimidines and their corresponding cycloalkane ring-fused derivatives as …

AEM Abdallah, GH Elgemeie - Drug design, development and …, 2018 - Taylor & Francis
Background Over the years, pyrazolopyrimidine derivatives have been recognized as
having antimicrobial activities. Recently, we reported different synthetic methods to prepare …