Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …

Malaria, which is caused by infection of red blood cells with Plasmodium parasites, can be
fatal in non-immune individuals if left untreated. The recent approval of the pre-erythrocytic …

Although malaria remains a big burden to many countries that it threatens their socio-
economic stability, particularly in the countries where malaria is endemic, there have been …

Background Surrogates of antiviral efficacy are needed for COVID-19. We aimed to
investigate the relationship between the virological effect of treatment and clinical efficacy as …

Oyster mushrooms form an integral part of many diets owing to their characteristic aroma,
delicious taste and nutraceutical value. In this study, we examined oyster mushrooms by …

Introduction Malaria remains a devastating infectious disease with hundreds of thousands of
casualties each year. Antimalarial drug resistance has been a threat to malaria control and …

New drugs with novel modes of action are needed to safeguard malaria treatment. In recent
years, millions of compounds have been tested for their ability to inhibit the growth of …

Background Severe malaria is a life-threatening infection, particularly affecting children
under the age of 5 years in Africa. Current treatment with parenteral artemisinin derivatives …

The coronavirus pandemic outbreak of 2019 highlighted the critical importance of
preparedness for current and future public health threats (https://www. mmv. org/mmv …

Background Novel antimalarials are needed to address emerging resistance to artemisinin
and partner drugs. We did two trials to evaluate safety, tolerability, pharmacokinetics, and …