The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction

N Hoshyar, S Gray, H Han, G Bao - Nanomedicine, 2016 - Taylor & Francis
Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …

Nanoparticle vaccines against infectious diseases

R Pati, M Shevtsov, A Sonawane - Frontiers in immunology, 2018 - frontiersin.org
Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …

Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

Peptide-based synthetic vaccines

M Skwarczynski, I Toth - Chemical science, 2016 - pubs.rsc.org
Classically all vaccines were produced using live or attenuated microorganisms or parts of
them. However, the use of whole organisms, their components or the biological process for …

Minireview: nanoparticles and the immune system

BS Zolnik, Á González-Fernández, N Sadrieh… - …, 2010 - academic.oup.com
Today nanotechnology is finding growing applications in industry, biology, and medicine.
The clear benefits of using nanosized products in various biological and medical …

Nanotoxicity: an interplay of oxidative stress, inflammation and cell death

P Khanna, C Ong, BH Bay, GH Baeg - Nanomaterials, 2015 - mdpi.com
Nanoparticles are emerging as a useful tool for a wide variety of biomedical, consumer and
instrumental applications that include drug delivery systems, biosensors and environmental …

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo

K Niikura, T Matsunaga, T Suzuki, S Kobayashi… - ACS …, 2013 - ACS Publications
This paper demonstrates how the shape and size of gold nanoparticles (AuNPs) affect
immunological responses in vivo and in vitro for the production of antibodies for West Nile …

Nanoparticle-based immunotherapy for cancer

K Shao, S Singha, X Clemente-Casares, S Tsai… - ACS …, 2015 - ACS Publications
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

Polymeric nanoparticle vaccines to combat emerging and pandemic threats

D Wibowo, SHT Jorritsma, ZJ Gonzaga, B Evert… - Biomaterials, 2021 - Elsevier
Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …