Cyclodextrin complexes: Perspective from drug delivery and formulation

S Jacob, AB Nair - Drug development research, 2018 - Wiley Online Library
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

[HTML][HTML] Drug delivery systems for prolonged duration local anesthesia

CM Santamaria, A Woodruff, R Yang, DS Kohane - Materials Today, 2017 - Elsevier
Numerous drug delivery systems have been applied to the problem of providing prolonged
duration local anesthesia (PDLA). Here we review the rationale for PDLA, the desirable …

High-fat diet changes fungal microbiomes and interkingdom relationships in the murine gut

T Heisel, E Montassier, A Johnson, G Al-Ghalith… - MSphere, 2017 - journals.asm.org
Dietary fat intake and shifts in gut bacterial community composition are associated with the
development of obesity. To date, characterization of microbiota in lean versus obese …

Preparation and characterization of inclusion complexes of naringenin with β-cyclodextrin or its derivative

LJ Yang, SX Ma, SY Zhou, W Chen, MW Yuan… - Carbohydrate …, 2013 - Elsevier
The inclusion complexation behavior, characterization and binding ability of naringenin with
β-cyclodextrin and its derivatives were investigated in both solution and the solid state by …

l-Diphenylalanine Microtubes As a Potential Drug-Delivery System: Characterization, Release Kinetics, and Cytotoxicity

RF Silva, DR Araújo, ER Silva, RA Ando, WA Alves - Langmuir, 2013 - ACS Publications
Microtubes obtained from the self-assembly of l-diphenylalanine (FF-MTs) were evaluated
as potential vehicles for drug delivery. The biological marker Rhodamine B (RhB) was …

Poloxamer 407/188 binary thermosensitive hydrogels as delivery systems for infiltrative local anesthesia: Physico-chemical characterization and pharmacological …

ACS Akkari, JZB Papini, GK Garcia… - Materials Science and …, 2016 - Elsevier
In this study, we reported the development and the physico-chemical characterization of
poloxamer 407 (PL407) and poloxamer 188 (PL188) binary systems as hydrogels for …

Characteristic of cyclodextrins: Their role and use in the pharmaceutical technology

M Lachowicz, A Stańczak… - Current Drug Targets, 2020 - ingentaconnect.com
About 40% of newly-discovered entities are poorly soluble in water, and this may be an
obstacle in the creation of new drugs. To address this problem, the present review article …

[HTML][HTML] Fabrication of fucoxanthin/2-hydroxypropyl-β-cyclodextrin inclusion complex assisted by ultrasound procedure to enhance aqueous solubility, stability and …

X Sun, J Zhu, C Liu, D Wang, CY Wang - Ultrasonics Sonochemistry, 2022 - Elsevier
Fucoxanthin (Fx) possesses multiple bioactivities such as antitumor, antioxidant and anti-
inflammatory activities, but its application is limited due to the poor water solubility, low …

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

P Papakyriakopoulou, K Manta, C Kostantini… - International Journal of …, 2021 - Elsevier
Quercetin, a flavonoid with possible neuroprotective action has been recently suggested for
the early-stage treatment of Alzheimer's disease. The low solubility and extended first pass …

Novel vitamin and gold-loaded nanofiber facial mask for topical delivery

A Fathi-Azarbayjani, L Qun, YW Chan, SY Chan - Aaps Pharmscitech, 2010 - Springer
Abstract l-ascorbic acid has been widely used in cosmetic and dermatological products
because of its ability to scavenge free radicals and destroy oxidizing agents. However, it is …