Adaptive immune receptor repertoire analysis
B cell and T cell receptor repertoires compose the adaptive immune receptor repertoire
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …
(AIRR) of an individual. The AIRR is a unique collection of antigen-specific receptors that …
Predictability of antigen binding based on short motifs in the antibody CDRH3
Adaptive immune receptors, such as antibodies and T-cell receptors, recognize foreign
threats with exquisite specificity. A major challenge in adaptive immunology is discovering …
threats with exquisite specificity. A major challenge in adaptive immunology is discovering …
Simulation of adaptive immune receptors and repertoires with complex immune information to guide the development and benchmarking of AIRR machine learning
Machine-learning methods (ML) have shown great potential in the adaptive immune
receptor repertoire (AIRR) field. However, there is a lack of large-scale ground-truth …
receptor repertoire (AIRR) field. However, there is a lack of large-scale ground-truth …