Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Interaction of the M-protein of group A Streptococcus (GAS) with its numerous host binding
partners might assist the bacteria in evading host immune responses. Although the …

Streptococcus pyogenes ranks among the main causes of mortality from bacterial infections
worldwide. Currently there is no vaccine to prevent diseases such as rheumatic heart …

Abstract Group A Streptococcus (GAS) M protein is an important virulence factor and
potential vaccine antigen, and constitutes the basis for strain ty** (emm-ty**). Although> …

While the incidence of many diseases has declined in developed countries, regions of the
world with low income and poor infrastructure continue to suffer a high burden of …

The available data support the hypothesis that group A streptococcal impetigo plays a role in
the pathogenesis of RHD. There is considerable scope to investigate this question through …

There is a pressing need to reduce the high global disease burden of rheumatic heart
disease (RHD) and its harbinger, acute rheumatic fever (ARF). ARF is a classical example of …

Background Group A streptococcus (GAS) is a serious human pathogen that affects people
of different ages and socio-economic levels. Although vaccination is potentially one of the …

Group A Streptococcus (GAS) infection can cause a variety of diseases in humans, ranging
from common sore throats and skin infections, to more invasive diseases and life …

Among clinically isolated β-hemolytic streptococci, Streptococcus pyogenes and S.
agalactiae were considered the main pathogens in humans until recently. In 1996, S …