Inflammation during the life cycle of the atherosclerotic plaque

P Libby - Cardiovascular Research, 2021 - academic.oup.com
Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed,
inflammatory mediators likely link many traditional and emerging risk factors with …

Clinical utility of polygenic risk scores for coronary artery disease

D Klarin, P Natarajan - Nature Reviews Cardiology, 2022 - nature.com
Over the past decade, substantial progress has been made in the discovery of alleles
contributing to the risk of coronary artery disease. In addition to providing causal insights into …

Low-attenuation noncalcified plaque on coronary computed tomography angiography predicts myocardial infarction: results from the multicenter SCOT-HEART trial …

MC Williams, J Kwiecinski, M Doris, P McElhinney… - Circulation, 2020 - Am Heart Assoc
Background: The future risk of myocardial infarction is commonly assessed using
cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis …

The National Lipid Association scientific statement on coronary artery calcium scoring to guide preventive strategies for ASCVD risk reduction

CE Orringer, MJ Blaha, R Blankstein, MJ Budoff… - Journal of clinical …, 2021 - Elsevier
Abstract An Expert Panel of the National Lipid Association reviewed the evidence related to
the use of coronary artery calcium (CAC) scoring in clinical practice for adults seen for …

Role of coronary artery calcium score in the primary prevention of cardiovascular disease

K Nasir, M Cainzos-Achirica - Bmj, 2021 - bmj.com
First developed in 1990, the Agatston coronary artery calcium (CAC) score is an
international guideline-endorsed decision aid for further risk assessment and personalized …

Assessment of cardiovascular disease risk: a 2022 update

E Goldsborough, N Osuji… - … and Metabolism Clinics, 2022 - endo.theclinics.com
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, with
atherosclerotic cardiovascular disease (ASCVD) being the dominant cause of total CVD …

Very high coronary artery calcium (≥ 1000) and association with cardiovascular disease events, non–cardiovascular disease outcomes, and mortality: results from …

AW Peng, ZA Dardari, RS Blumenthal, O Dzaye… - Circulation, 2021 - Am Heart Assoc
Background: There are limited data on the unique cardiovascular disease (CVD), non-CVD,
and mortality risks of primary prevention individuals with very high coronary artery calcium …

Distribution of coronary artery calcium by age, sex, and race among patients 30-45 years old

A Javaid, ZA Dardari, JD Mitchell, SP Whelton… - Journal of the American …, 2022 - jacc.org
Background Coronary artery calcium (CAC) is a measure of atherosclerotic burden and is
well-validated for risk stratification in middle-to older-aged adults. Few studies have …

Association of coronary artery calcium detected by routine ungated CT imaging with cardiovascular outcomes

AW Peng, R Dudum, SS Jain, DJ Maron… - Journal of the American …, 2023 - jacc.org
Background Coronary artery calcium (CAC) is a strong predictor of cardiovascular events
across all racial and ethnic groups. CAC can be quantified on nonelectrocardiography …

Coronary artery calcium scoring: new insights into clinical interpretation—lessons from the CAC Consortium

S Adelhoefer, SMI Uddin, AD Osei… - Radiology …, 2020 - pubs.rsna.org
Coronary artery calcium (CAC) is a highly specific marker for coronary atherosclerosis. The
CAC Consortium, a multicenter, retrospective, real-world cohort study, was established to …