The high mobility group protein 2 (HMGA2) regulates gene expression by binding to AT-rich
regions of DNA. Akin to other DNA architectural proteins, HMGA2 is highly expressed in …

We previously reported that the chromatin high-mobility group protein 1 (HMG-1) enhances
the sequence-specific DNA binding activity of progesterone receptor (PR) in vitro, thus …

Ribosomal transcription in mammals is regulated in response to growth, differentiation,
disease, and aging, but the mechanisms of this regulation have remained unresolved. We …

The high mobility group (HMG) chromosomal proteins, which are common to all eukaryotes,
bind DNA in a non-sequence-specific fashion to promote chromatin function and gene …

To clarify the physical basis of DNA binding specificity, the thermodynamic properties and
DNA binding and bending abilities of the DNA binding domains (DBDs) of sequence …

Cisplatin is an effective agent for the treatment of testicular cancer. In the present study with
mouse testicular teratocarcinoma cell extracts, we observed a deficiency in nucleotide …

HMG1 is an evolutionarily highly conserved chromosomal protein consisting of two folded
DNA-binding domains, A and B (" high mobility group (HMG) boxes"), and an acidic C …

Publisher Summary Steroid hormones exert their major biological effects on differentiation,
growth, homeostasis, and behavior by binding to nuclear receptors, which, in turn, regulate …

The thermal properties of two forms of the Drosophila melanogaster HMG-D protein, with
and without its highly basic 26 residue C-terminal tail (D100 and D74) and the …

The HMG box is an 80 amino acid domain found in a variety of eukaryotic chromosomal
proteins and transcription factors. Binding to DNA is associated with recognition of structural …