Iron as an important element plays crucial roles in various physiological and pathological
processes. Iron metabolism behaves in systemic and cellular two levels that usually are in …

Iron is an essential dietary element. However, the ability of iron to cycle between oxidized
and reduced forms also renders it capable of contributing to free radical formation, which …

Demanded as an essential trace element that supports cell growth and basic functions, iron
can be harmful and cancerogenic though. By exchanging between its different oxidized …

Iron is essential for several vital biological processes. Its deficiency or overload drives to the
development of several pathologies. To maintain iron homeostasis, the organism controls …

Abstract The transferrin receptor (TfR1), which mediates cellular iron uptake through clathrin-
dependent endocytosis of iron-loaded transferrin, plays a key role in iron homeostasis …

MicroRNAs (miRNAs) are small non-coding, endogenous, single-stranded RNAs. MiRNAs
have been implicated in different areas such as the immune response, neural development …

Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal
role in intercellular communication by regulating recipient cell gene expression and affecting …

Prostate cancer (PCa) is a leading cause of mortality and morbidity in men worldwide, and
emerging evidence suggests that the CD44 high prostate tumor-initiating cells (TICs) are …

Background Breast milk contains complex nutrients and facilitates the maturation of various
biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in …

Aquaporins facilitate efficient diffusion of water across cellular membranes, and water
homeostasis is critically important in conditions such as cerebral edema. Changes in …