Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Compensate for or minimize matrix effects? Strategies for overcoming matrix effects in liquid chromatography-mass spectrometry technique: a tutorial review

M Cortese, MR Gigliobianco, F Magnoni, R Censi… - Molecules, 2020 - mdpi.com
In recent decades, mass spectrometry techniques, particularly when combined with
separation methods such as high-performance liquid chromatography, have become …

[BUCH][B] Handbook of cyanobacterial monitoring and cyanotoxin analysis

J Meriluoto, L Spoof, GA Codd - 2017 - books.google.com
A valuable handbook containing reviews, practical methods and standard operating
procedures. A valuable and practical working handbook containing introductory and …

Ion suppression; a critical review on causes, evaluation, prevention and applications

A Furey, M Moriarty, V Bane, B Kinsella, M Lehane - Talanta, 2013 - Elsevier
The consequences of matrix effects in mass spectrometry analysis are a major issue of
concern to analytical chemists. The identification of any ion suppressing (or enhancing) …

Biological matrix effects in quantitative tandem mass spectrometry-based analytical methods: advancing biomonitoring

P Panuwet, RE Hunter Jr, PE D'Souza… - Critical reviews in …, 2016 - Taylor & Francis
The ability to quantify levels of target analytes in biological samples accurately and precisely
in biomonitoring involves the use of highly sensitive and selective instrumentation such as …

An overview of matrix effects in liquid chromatography–mass spectrometry

H Trufelli, P Palma, G Famiglini… - Mass spectrometry …, 2011 - Wiley Online Library
Matrix‐dependent signal suppression or enhancement represents a major drawback in
quantitative analysis with liquid chromatography coupled to atmospheric pressure ionization …

Overcoming matrix effects using the dilution approach in multiresidue methods for fruits and vegetables

C Ferrer, A Lozano, A Agüera, AJ Girón… - … of Chromatography A, 2011 - Elsevier
During recent years matrix effects in liquid chromatography coupled to tandem mass
spectrometry (LC–MS/MS) have quickly become a major concern in food analysis. The …

Deuterium‐und tritiummarkierte Verbindungen: Anwendungen in den modernen Biowissenschaften

J Atzrodt, V Derdau, WJ Kerr, M Reid - Angewandte Chemie, 2018 - Wiley Online Library
Wasserstoffisotope sind einzigartige Werkzeuge zur Identifizierung und Erforschung
biologischer oder chemischer Vorgänge. Wasserstoffisotopenmarkierungen erlauben den …

Validation of bioanalytical LC–MS/MS assays: evaluation of matrix effects

A Van Eeckhaut, K Lanckmans, S Sarre… - … of Chromatography B, 2009 - Elsevier
Liquid chromatography coupled to atmospheric pressure ionization tandem mass
spectrometry is currently the method of choice for the quantitative determination of drugs in …

Matrix effects demystified: Strategies for resolving challenges in analytical separations of complex samples

ML Williams, AA Olomukoro… - Journal of …, 2023 - Wiley Online Library
Matrix effects can significantly impede the accuracy, sensitivity, and reliability of separation
techniques presenting a formidable challenge to the analytical process. It is crucial to …