Microfluidic cell cultures are ideally positioned to become the next generation of in vitro
diagnostic tools for biomedical research, where key biological processes such as cell …

Vascularization plays a crucial role in transporting and exchanging nutrients and oxygen
between implanted grafts with the host tissue. In the biofabrication of the implanted grafts …

Pathological scarring imposes a major clinical and social burden worldwide. Human
cutaneous wounds are responsive to mechanical forces and convert mechanical cues to …

The combination of microfabrication-based technologies with cell biology has laid the
foundation for the development of advanced in vitro diagnostic systems capable of analyzing …

Stem cell transplantation is an appealing potential therapy for vascular diseases and an
indispensable key step in vascular tissue engineering. Substantial effort has been made to …

Heart diseases are one of the main causes of death around the world. The great challenge
for scientists is to develop new therapeutic methods for these types of ailments. Stem cells …

Mesenchymal stem cells (MSCs) are among the most promising and suitable stem cell types
for vascular tissue engineering. Substantial effort has been made to differentiate MSCs …

Since human skin is the primary interface responding to external mechanical stimuli,
extrinsic forces can disrupt its balanced microenvironment and lead to cutaneous lesions …

Endothelial cells play a crucial role in the arterial homeostasis. In addition to physiological
risk factors, abnormal levels of hemodynamic parameters induced by the pulsatile flow …

Mechanical stimuli are important in directing the fate of stem cells; the effects of mechanical
stimuli reported in recent research are reviewed here. Stem cells normally undergo two …