Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

Optical coherence tomography (OCT) is widely used for biomedical imaging and clinical
diagnosis. However, speckle noise is a key factor affecting OCT image quality. Here, we …

Cardiovascular disease is the leading cause of morbidity and mortality in the United States.
Knowledge of a patient's heart structure will help to plan procedures, potentially identifying …

The heart of the fruit fly, Drosophila melanogaster, is a particularly suitable model for cardiac
studies. Optical coherence microscopy (OCM) captures in vivo cross-sectional videos of the …

In order to facilitate cardiovascular research to develop non-invasive optical heart pacing
methods, we have generated a double-transgenic Drosophila melanogaster (fruit fly) model …

Drosophila is a powerful genetic model system for cardiovascular studies. Recently,
optogenetic pacing tools have been developed to control Drosophila heart rhythm …

Using Drosophila melanogaster (fruit fly) as a model organism has ensured significant
progress in many areas of biological science, from cellular organization and genomic …

A custom convolutional neural network (CNN) integrated with convolutional long short-term
memory (LSTM) achieves accurate 3D (2D+ time) segmentation in cross-sectional videos of …

Optical coherence microscopy (OCM) imaging of the Drosophila melanogaster (fruit fly)
heart tube has enabled the non-invasive characterization of fly heart physiology in vivo …

ABSTRACT A severe form of infantile cardiomyopathy (CM) has been linked to mutations in
ELAC2, a highly conserved human gene. It encodes Zinc phosphodiesterase ELAC protein …