Ectopic odorant receptors responding to flavor compounds in skin health and disease: Current insights and future perspectives

R Geng, Y Wang, J Fang, Y Zhao, M Li… - Critical Reviews in …, 2023 - Taylor & Francis
Skin, the largest organ of human body, acts as a barrier to protect body from the external
environment and is exposed to a myriad of flavor compounds, especially food-and plant …

Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms

H Lin, Q You, X Wei, Z Chen, X Wang - The American Journal of …, 2024 - World Scientific
Osthole, a coumarin compound mainly derived from Cnidium monnieri (L.), has attracted
much interest from the scientific community owing to its multiple therapeutic properties …

Tenebrio molitor Larva Trypsin Hydrolysate Ameliorates Atopic Dermatitis in C57BL/6 Mice by Targeting the TLR-Mediated MyD88-Dependent MAPK Signaling …

M Fan, NE Wedamulla, YJ Choi, Q Zhang, SM Bae… - Nutrients, 2022 - mdpi.com
Atopic dermatitis (AD) is a widely researched chronic inflammatory skin disease with a
complex etiology. The increased prevalence of AD necessitates exploration of natural …

The effect of osthole on transient receptor potential channels: a possible alternative therapy for atopic dermatitis

NK Kordulewska, A Król-Grzymała - Journal of Inflammation …, 2024 - Taylor & Francis
Introduction Chronic recurrent skin inflammation and severe itching in patients with atopic
dermatitis (AD) significantly impair their quality of life. The H4 histamine receptor plays a key …

The role of Toll-like receptors in the pathogenesis of atopic dermatitis

A Vafaeian, F Rajabi, N Rezaei - Heliyon, 2025 - cell.com
Toll-like receptors (TLR), the key players of the innate immune system, contribute to the
pathogenesis of atopic dermatitis (AD) through multiple pathways. TLRs play a crucial role in …

[HTML][HTML] Protective and Anti-Inflammatory Effect of Novel Formulation Based on High and Low Molecular Weight Hyaluronic Acid and Salvia haenkei

M D'Agostino, AM Giori, V Vassallo, C Schiraldi… - International Journal of …, 2025 - mdpi.com
Salvia haenkei (SH-Haenkenium®), a native plant of Bolivia, is known as strong inhibitor of
senescence and recently exploited in wound healing and for its potential anti-inflammatory …

Chinese Herbal Medicine and Their Active Ingredients Involved in the Treatment of Atopic Dermatitis Related Signaling Pathways

W Nie, H Fu, Y Zhang, H Yang, B Liu - Phytotherapy Research, 2025 - Wiley Online Library
Atopic dermatitis (AD) is a common inflammatory dermatitis of the skin and poses
therapeutic challenges due to the adverse reactions and high costs associated with …

Effects of Gallus epidermal growth factor on immune function and intestinal development in male broilers

Y Jia, Q Huang, R Song, J Zhou, C Sun… - Journal of Applied Animal …, 2025 - Taylor & Francis
The present study aims to evaluate the effects of Gallus epidermal growth factor (gEGF) on
growth performance, immune function, intestinal barrier, and the inflammatory response in …

In vitro models for investigating itch

H Mießner, J Seidel, ESJ Smith - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Itch (pruritus) is a sensation that drives a desire to scratch, a behavior observed in many
animals. Although generally short-lasting and not causing harm, there are several …

[HTML][HTML] Osthole ameliorates chronic pruritus in 2, 4-dichloronitrobenzene-induced atopic dermatitis by inhibiting IL-31 production

S He, X Liang, W Chen, Y Nima, Y Li, Z Gu, S Lai… - Chinese Herbal …, 2024 - Elsevier
Objective This study aims to elucidate the therapeutic potential of osthole for the treatment of
atopic dermatitis (AD), focusing on its ability to alleviate chronic pruritus (CP) and the …