Heating technology for malignant tumors: A review

HP Kok, ENK Cressman, W Ceelen… - International Journal …, 2020 - Taylor & Francis
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …

A review of basic to clinical studies of irreversible electroporation therapy

C Jiang, RV Davalos, JC Bischof - IEEE Transactions on …, 2014 - ieeexplore.ieee.org
The use of irreversible electroporation (IRE) for cancer treatment has increased sharply over
the past decade. As a nonthermal therapy, IRE offers several potential benefits over other …

Selective modulation of intracellular effects of cells using pulsed electric fields

MB Sano, B Christopher, SS Verbridge… - US Patent …, 2019 - Google Patents
A system and method for selectively treating aberrant cells such as cancer cells through
administration of a train of electrical pulses is described. The pulse length and delay …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

Electroporation in food processing and biorefinery

S Mahnič-Kalamiza, E Vorobiev, D Miklavčič - The Journal of membrane …, 2014 - Springer
Electroporation is a method of treatment of plant tissue that due to its nonthermal nature
enables preservation of the natural quality, colour and vitamin composition of food products …

Modeling of electric field distribution in tissues during electroporation

S Corovic, I Lackovic, P Sustaric, T Sustar… - Biomedical engineering …, 2013 - Springer
Background Electroporation based therapies and treatments (eg electrochemotherapy, gene
electrotransfer for gene therapy and DNA vaccination, tissue ablation with irreversible …

A numerical investigation of the electric and thermal cell kill distributions in electroporation-based therapies in tissue

PA Garcia, RV Davalos, D Miklavcic - PloS one, 2014 - journals.plos.org
Electroporation-based therapies are powerful biotechnological tools for enhancing the
delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs) …

Tutorial: Electroporation of cells in complex materials and tissue

L Rems, D Miklavčič - Journal of Applied Physics, 2016 - pubs.aip.org
Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

Integration of very short electric pulses for minimally to noninvasive electroporation

R Davalos, B Christopher, J Caldwell - US Patent 8,926,606, 2015 - Google Patents
The present invention provides methods, devices, and sys tems for in vivo treatment of cell
proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors …

Nonthermal irreversible electroporation: fundamentals, applications, and challenges

A Golberg, ML Yarmush - IEEE Transactions on biomedical …, 2013 - ieeexplore.ieee.org
Tissue ablation is an essential procedure for the treatment of many diseases. In the last
decade, a nonthermal tissue ablation using intensive pulsed electric fields, called …