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Mitochondria in health, disease, and aging
JS Harrington, SW Ryter, M Plataki… - Physiological …, 2023 - journals.physiology.org
Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
D Liu, SY Huang, JH Sun, HC Zhang, QL Cai… - Military Medical …, 2022 - Springer
Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
[HTML][HTML] Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
Background Antimicrobial resistance (AMR) poses an important global health challenge in
the 21st century. A previous study has quantified the global and regional burden of AMR for …
the 21st century. A previous study has quantified the global and regional burden of AMR for …
International consensus criteria for pediatric sepsis and septic shock
Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-
specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the …
specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the …
The burden of bacterial antimicrobial resistance in the WHO African region in 2019: a cross-country systematic analysis
Background A critical and persistent challenge to global health and modern health care is
the threat of antimicrobial resistance (AMR). Previous studies have reported a …
the threat of antimicrobial resistance (AMR). Previous studies have reported a …
The pathophysiology of sepsis and precision-medicine-based immunotherapy
Sepsis remains a major cause of morbidity and mortality in both low-and high-income
countries. Antibiotic therapy and supportive care have significantly improved survival …
countries. Antibiotic therapy and supportive care have significantly improved survival …
[HTML][HTML] The burden of bacterial antimicrobial resistance in the WHO European region in 2019: a cross-country systematic analysis
Background Antimicrobial resistance (AMR) represents one of the most crucial threats to
public health and modern health care. Previous studies have identified challenges with …
public health and modern health care. Previous studies have identified challenges with …
[HTML][HTML] Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths …
the world. Previous publications have estimated the effect of AMR on incidence, deaths …
How to use biomarkers of infection or sepsis at the bedside: guide to clinicians
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …
response to infection. In this context, biomarkers could be considered as indicators of either …
Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis
Sepsis arises from diverse and incompletely understood dysregulated host response
processes following infection that leads to life-threatening organ dysfunction. Here we …
processes following infection that leads to life-threatening organ dysfunction. Here we …