The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Pancreatic ductal adenocarcinoma (PDAC) is frequently detected in late stages, which leads
to limited therapeutic options and a dismal overall survival rate. To date, no robust method …

Pancreatic cancer (PC) is one of the most lethal malignancies. Recent studies indicate that
patients with incidentally diagnosed PC have better prognosis than those with symptoms …

Background Despite improvements in cancer management, most pancreatic cancers are still
diagnosed at an advanced stage. We have recently identified promoter DNA methylation of …

Pancreatic cancer is currently the most lethal tumor entity and case numbers are rising. It will
soon be the second most frequent cause of cancer-related death in the Western world …

Pancreatic cancer (PC) is one of the most aggressive forms of cancer. Negative prognosis is
mainly due to the late diagnosis in advanced stages, when the disease is already …

DNA methylation profiles are in dynamic equilibrium via the initiation of methylation,
maintenance of methylation and demethylation, which control gene expression and …

ADAMTSs (A disintegrin and metalloprotease domains with thrombospondins motifs) are
complex extracellular proteases that have been related to both oncogenic and tumor …

Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer
and has a 5-year survival of< 5%. Only about 15% of the patients present with a resectable …

Simple Summary Chronic alcoholic pancreatitis displays a cumulative risk of pancreatic
cancer estimated at 4% after 15 to 20 years, this risk being higher for hereditary pancreatitis …