Relapse after electric barrier-induced voluntary abstinence: A review

K Negishi, I Fredriksson, JM Bossert, A Zangen… - Current Opinion in …, 2024 - Elsevier
Relapse to drug use during abstinence is a defining feature of addiction. To date, however,
results from studies using rat relapse/reinstatement models have yet to result in FDA …

Drug discrimination learning: Interoceptive stimulus control of behavior and its implications for regulated and dysregulated drug intake

S Huang, AL Riley - Pharmacology Biochemistry and Behavior, 2024 - Elsevier
Drug discrimination research has generated rich evidence for the capacity of interoceptive
drug stimuli to control behavior by serving as discriminative cues. Owing to its …

Relapse after intermittent access to cocaine: Discriminative cues more effectively trigger drug seeking than do conditioned cues

NA Ndiaye, SA Shamleh, D Casale… - …, 2024 - Springer
Rationale When people with drug addiction encounter cues associated with drug use, this
can trigger cravings and relapse. These cues can include conditioned stimuli (CSs) …

Delineating anticipatory arousal from reward consumption: evaluating fixed-intervals in cocaine seeking-taking response chains

MZ Leonard, KA Miczek, HE Covington III - Psychopharmacology, 2024 - Springer
Rationale Anticipation is a critical antecedent to drug use, in which the prospect of imminent
drug availability can potently motivate instrumental actions directed to procure it. Models that …

Valence ambiguity dynamically shapes striatal dopamine heterogeneity

KN Bornhoft, J Prohofsky, TJ O'Neal, AR Wolff… - bioRxiv, 2024 - biorxiv.org
Adaptive decision making relies on dynamic updating of learned associations where
environmental cues come to predict positive and negatively valenced stimuli, such as food …

Triggered Temptations: A New Procedure to Compare Reward-Seeking Behaviour Induced by Discriminative and Conditioned Stimuli in Rats

MR LeCocq, S Najafipashaki, D Casale, I Laplante… - bioRxiv, 2024 - biorxiv.org
Rationale: Environmental cues guide animals towards resources vital for survival but can
also drive maladaptive reward-seeking behaviours, as in gambling and eating disorders …

Activation of Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Reward Seeking Triggered by Discriminative Stimuli

MR LeCocq, A Mainville-Berthiaume, I Laplante… - bioRxiv, 2024 - biorxiv.org
Reward-associated cues are essential in guiding reward-seeking behaviours. These cues
include conditioned stimuli (CSs) which occur following seeking actions and indicate reward …

L'accès intermittent pour modéliser l'addiction à la cocaïne chez la rate: études sur des traitements pharmacologiques et des processus de rechute

NA Ndiaye - 2024 - papyrus.bib.umontreal.ca
Il n'existe aucun traitement médicamenteux approuvé contre l'addiction à la cocaïne. La
cocaïne est l'une des drogues les plus consommées dans le monde, mais peu de …