Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine

RM Samsonraj, M Raghunath… - Stem cells …, 2017 - academic.oup.com
Mesenchymal stem cells (MSC) hold great potential for regenerative medicine because of
their ability for self-renewal and differentiation into tissue-specific cells such as osteoblasts …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro …

J Kobolak, A Dinnyes, A Memic, A Khademhosseini… - Methods, 2016 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells. Although they were originally
identified in bone marrow and described as 'marrow stromal cells', they have since been …

Mesenchymal stem cells as a cornerstone in a galaxy of intercellular signals: basis for a new era of medicine

S Fernández-Francos, N Eiro, LA Costa… - International Journal of …, 2021 - mdpi.com
Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Mesenchymal markers on human adipose stem/progenitor cells

L Zimmerlin, VS Donnenberg, JP Rubin… - Cytometry Part …, 2013 - Wiley Online Library
The stromal‐vascular fraction (SVF) of adipose tissue is a rich source of multipotent stem
cells. We and others have described three major populations of stem/progenitor cells in this …

Human adult stem cells from diverse origins: an overview from multiparametric immunophenoty** to clinical applications

BR Sousa, RC Parreira, EA Fonseca… - Cytometry Part …, 2014 - Wiley Online Library
Stem cells are known for their capacity to self‐renew and differentiate into at least one
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …

Exosomes derived from miR-34a-overexpressing mesenchymal stem cells inhibit in vitro tumor growth: A new approach for drug delivery

F Vakhshiteh, S Rahmani, SN Ostad, Z Madjd… - Life Sciences, 2021 - Elsevier
Aims Exosomes hold great promise as bio-inspired delivery vehicles. Mesenchymal stem
cells (MSCs) are recognized for their potential to yield huge quantities of exosomes. We …

[HTML][HTML] Mesenchymal stem cells in homeostasis and systemic diseases: hypothesis, evidences, and therapeutic opportunities

FJ Vizoso, N Eiro, L Costa, P Esparza… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known
function in tissue regeneration. However, there is also evidence indicating a broader role of …

A comparison of the use of adipose-derived and bone marrow-derived stem cells for peripheral nerve regeneration in vitro and in vivo

LN Zhou, JC Wang, PLM Zilundu, YQ Wang… - Stem cell research & …, 2020 - Springer
Background To date, it has repeatedly been demonstrated that infusing bone marrow-
derived stem cells (BMSCs) into acellular nerve scaffolds can promote and support axon …