Biological action of singlet molecular oxygen from the standpoint of cell signaling, injury and death

J Fujii, Y Soma, Y Matsuda - Molecules, 2023 - mdpi.com
Energy transfer to ground state triplet molecular oxygen results in the generation of singlet
molecular oxygen (1O2), which has potent oxidizing ability. Irradiation of light, notably …

[HTML][HTML] Interplay of mitochondrial calcium signalling and reactive oxygen species production in the brain

PR Angelova, AY Abramov - Biochemical Society Transactions, 2024 - portlandpress.com
Intracellular communication and regulation in brain cells is controlled by the ubiquitous
Ca2+ and by redox signalling. Both of these independent signalling systems regulate most …

Iridium (III)-Based Infrared Two-Photon Photosensitizers: Systematic Regulation of Their Photodynamic Therapy Efficacy

XL Li, LZ Zeng, R Yang, XD Bi, Y Zhang… - Inorganic …, 2023 - ACS Publications
Cyclometalated iridium (III) complexes are of significant importance in the field of antitumor
photodynamic therapy (PDT), whether they exist as single molecules or are incorporated …

Heterometallic ruthenium–osmium complexes: dual photodynamic and photothermal therapy for melanoma and drug-resistant lung tumour in vivo

YA Deng, SJ Tang, MF Wang, X Ren, XL Li… - Inorganic Chemistry …, 2023 - pubs.rsc.org
A series of hetero-dinuclear Ru–Os complexes have been constructed by combining
mononuclear modules derived from homo-dinuclear Ru–Ru complexes with dual PDT/PTT …

Bleeding the Excited State Energy to the Utmost: Single‐Molecule Iridium Complexes for In Vivo Dual Photodynamic and Photothermal Therapy by an Infrared Low …

SJ Tang, QF Li, MF Wang, R Yang… - Advanced …, 2023 - Wiley Online Library
A series of cyclometalated Ir (III) complexes with morpholine and piperazine groups are
designed as dual photosensitizers and photothermal agents for more efficient antitumor …

Efficiency of direct photoinduced generation of singlet oxygen at different wavelengths, power density and exposure time of laser irradiation

I Makovik, A Vinokurov, A Dunaev, E Rafailov… - Analyst, 2023 - pubs.rsc.org
This work investigates the influence of laser irradiation parameters (wavelength, power
density and exposure time) on singlet oxygen (1O2) generation efficiency. Chemical trap (L …

An amplification mechanism for weak ELF magnetic fields quantum-bio effects in cancer cells

A Zandieh, SP Shariatpanahi, AA Ravassipour… - Scientific Reports, 2025 - nature.com
Observing quantum mechanical characteristics in biological processes is a surprising and
important discovery. One example, which is gaining more experimental evidence and …

Direct laser-induced singlet oxygen in biological systems: application from in vitro to in vivo

V Dremin… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
In recent years, there has been increasing interest in the singlet form of oxygen as a
regulator of the physiological functions of cells. The use of photosensitisers is a classical …

Point of No Return—What Is the Threshold of Mitochondria With Permeability Transition in Cells to Trigger Cell Death

KA Kritskaya, OA Stelmashchuk… - Journal of Cellular …, 2025 - Wiley Online Library
Programmed cell death (apoptosis) is essential part of the process of tissue regeneration
that also plays role in the mechanism of pathology. The phenomenon of fast and transient …

Cell-Permeable HSP70 Protects Neurons and Astrocytes Against Cell Death in the Rotenone-Induced and Familial Models of Parkinson's Disease

AY Vinokurov, AA Palalov, KA Kritskaya… - Molecular …, 2024 - Springer
Abstract Heat shock protein 70 (HSP70) is activated under stress response. Its involvement
in cell protection, including energy metabolism and quality control makes it a promising …