The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021‏ - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Oxidative stress response pathways in fungi

H Yaakoub, S Mina, A Calenda, JP Bouchara… - Cellular and molecular …, 2022‏ - Springer
Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Mechanisms of antifungal drug resistance

LE Cowen, D Sanglard… - Cold Spring …, 2015‏ - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012‏ - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans

A da Silva Dantas, A Day, M Ikeh, I Kos, B Achan… - Biomolecules, 2015‏ - mdpi.com
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

D Sanglard, A Coste, S Ferrari - FEMS yeast research, 2009‏ - academic.oup.com
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …

Stress adaptation in a pathogenic fungus

AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014‏ - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …

Candida albicans: A Model Organism for Studying Fungal Pathogens

MA Kabir, MA Hussain, Z Ahmad - … Scholarly Research Notices, 2012‏ - Wiley Online Library
Candida albicans is an opportunistic human fungal pathogen that causes candidiasis. As
healthcare has been improved worldwide, the number of immunocompromised patients has …

Update on antifungal drug resistance

DS Perlin, E Shor, Y Zhao - Current clinical microbiology reports, 2015‏ - Springer
Invasive fungal infections remain a major source of global morbidity and mortality, especially
among patients with underlying immune suppression. Successful patient management …

Regulation of multidrug resistance in pathogenic fungi

J Morschhäuser - Fungal Genetics and Biology, 2010‏ - Elsevier
Infections by opportunistic pathogenic fungi, especially Candida species, Cryptococcus
neoformans, and Aspergillus fumigatus, are a serious medical problem in …