Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Sepsis biomarkers and diagnostic tools with a focus on machine learning

M Komorowski, A Green, KC Tatham, C Seymour… - …, 2022 - thelancet.com
Over the last years, there have been advances in the use of data-driven techniques to
improve the definition, early recognition, subtypes characterisation, prognostication and …

Heterogeneity in sepsis: new biological evidence with clinical applications

A Leligdowicz, MA Matthay - Critical care, 2019 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2019. Other selected articles can be found online at https://www …

Biomarkers in pneumonia—beyond procalcitonin

M Karakioulaki, D Stolz - International journal of molecular sciences, 2019 - mdpi.com
Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …

Biomarkers in sepsis

TSR Van Engelen, WJ Wiersinga… - Critical care …, 2018 - criticalcare.theclinics.com
Sepsis is characterized by complex pathophysiology and heterogeneous phenotypes of
affected patients regarding their symptoms, response to treatment, and outcomes. At present …

Prediction of sepsis mortality using metabolite biomarkers in the blood: a meta-analysis of death-related pathways and prospective validation

J Wang, Y Sun, S Teng, K Li - BMC medicine, 2020 - Springer
Background Sepsis is a leading cause of death in intensive care units (ICUs), but outcomes
of individual patients are difficult to predict. The recently developed clinical metabolomics …

Metabolomics meets systems immunology

J Fu, F Zhu, CJ Xu, Y Li - EMBO reports, 2023 - embopress.org
Metabolic processes play a critical role in immune regulation. Metabolomics is the
systematic analysis of small molecules (metabolites) in organisms or biological samples …

A targeted metabolomics approach for sepsis-induced ARDS and its subphenotypes

Y Chang, HJ Yoo, SJ Kim, K Lee, CM Lim, SB Hong… - Critical Care, 2023 - Springer
Background Acute respiratory distress syndrome (ARDS) is etiologically and clinically a
heterogeneous disease. Its diagnostic characteristics and subtype classification, and the …

Protective effect of isosteviol sodium against LPS-induced multiple organ injury by regulating of glycerophospholipid metabolism and reducing macrophage-driven …

S Wang, KS Tan, H Beng, F Liu, J Huang, Y Kuai… - Pharmacological …, 2021 - Elsevier
Sepsis is a severe inflammatory disorder that can lead to multiple organ injury. Isosteviol
sodium (STV-Na) is a terpenoid derived from stevioside that exerts anti-inflammatory …

[HTML][HTML] Current aspects in sepsis approach. Turning things around

FJ Candel, MB Sá, S Belda, G Bou… - Revista Española de …, 2018 - ncbi.nlm.nih.gov
The incidence and prevalence of sepsis depend on the definitions and records that we use
and we may be underestimating their impact. Up to 60% of the cases come from the …