Comparison of the differences between two-photon excitation, Upconversion, and conventional photodynamic therapy on cancers in in vitro and in vivo studies

C Xu, SK Law, AWN Leung - Pharmaceuticals, 2024 - mdpi.com
Photodynamic therapy (PDT) is a minimally invasive treatment for several diseases. It
combines light energy with a photosensitizer (PS) to destroy the targeted cells or tissues. A …

Cascade Nanoreactor Employs Mitochondrial‐Directed Chemodynamic and δ‐ALA‐Mediated Photodynamic Synergy for Deep‐Seated Oral Cancer Therapy

Q Yin, J Zhang, H Zhang, J Gao, L Weng… - Advanced …, 2024 - Wiley Online Library
The management of oral squamous cell carcinoma (OSCC) poses significant challenges,
leading to organ impairment and ineffective treatment of deep‐seated tumors, adversely …

Engineering Tumor‐Specific Nanotheranostic Agent with MR Image‐Guided NIR‐II &‐III Photodynamic Therapy to Combat Against Deeply Seated Orthotopic …

K Nuthalapati, R Vankayala, M Shanmugam… - Small …, 2024 - Wiley Online Library
Glioblastoma multiforme (GBM) is one of the most aggressive, incurable, and difficult‐to‐
treat malignant brain tumor with very poor survival rates. The gold standard in treating GBMs …

Revolutionizing Cancer Management: Cutting-Edge Techniques for Nanophotosensitizer Delivery in Photodynamic Therapy

S Bhamble, K Kumar, P Datta, S Dighe… - Journal of Drug Delivery …, 2025 - Elsevier
Traditional modalities of cancer treatment often pose constrains due to non-specificity,
associated side effects, and risk of relapse. Given that, non-invasive light dependent …

Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms

G Zhao, Y Wang, Z Fan, J **ong, YN Ertas… - Cancer Letters, 2024 - Elsevier
Cancer is the result of genetic abnormalities that cause normal cells to grow into neoplastic
cells. Cancer is characterized by several distinct features, such as uncontrolled cell growth …

Near-Infrared Optogenetic Nanosystem for Spatiotemporal Control of CRISPR-Cas9 Gene Editing and Synergistic Photodynamic Therapy

J Zeng, X Huang, Y Yang, J Wang, Y Shi… - … Applied Materials & …, 2024 - ACS Publications
Controlling CRISPR/Cas9 gene editing at the spatiotemporal resolution level, especially for
in vivo applications, remains a great challenge. Here, we developed a near-infrared (NIR) …

Methylene blue loaded K 0.3 Bi 0.7 F 2.4: Yb, Er upconversion nanoparticles for near-infrared activated photodynamic therapy

M Bungla, P Sharma, A Shanavas… - New Journal of …, 2024 - pubs.rsc.org
Bismuth-based fluoride nanoparticles have received a lot of interest as host materials for
upconversion and have been recommended for lighting devices and biological applications …

Enhancing upconversion quantum yield by means of pulsed excitation modulation

KW Kho, S Riou, S Konugolu, K Komolibus, J Matias… - Optics …, 2025 - opg.optica.org
Upconversion luminescent nanomaterials have gained popularity recently due to their
multitude of features that are attractive to a wide range of applications in the biomedical field …

Near-Infrared Long Lifetime Upconversion Nanoparticles for Ultrasensitive microRNA Detection via Time-Gated Luminescence Resonance Energy Transfer

J Lee, S Kim, Y Park, J Han, H Kim, H Jang, MY Lee… - 2024 - researchsquare.com
Although upconversion nanoparticle (UCNP)-based luminescence resonance energy
transfer (LRET) biosensing offers advantages such as wash-free detection and precise …