BACKGROUND: The cytosolic glutathione transferases (GSTs) comprise a super family of
proteins that can be categorized into multiple classes with a mixture of highly specific and …

The glutathione transferases (GSTs) are one of the most important families of detoxifying
enzymes in nature. The classic activity of the GSTs is conjugation of compounds with …

Glutathione transferases (GSTs) represent a widespread multigenic enzyme family able to
modify a broad range of molecules. These notably include secondary metabolites and …

Plasma membrane channels have been extensively studied, and their physiological roles
are well established. In contrast, relatively little information is available about intracellular …

The β subunit of the Escherichia coli replicative DNA polymerase III holoenzyme is the
sliding clamp that interacts with the α (polymerase) subunit to maintain the high processivity …

The CLIC proteins are a highly conserved family of metazoan proteins with the unusual
ability to adopt both soluble and integral membrane forms. The physiological functions of …

Abstract Chloride Intracellular Channel (CLIC) family members uniquely transition between
soluble and membrane-associated conformations. Despite decades of extensive functional …

Chloride intracellular channel proteins (CLICs) differ from most ion channels as they can
exist in both soluble and integral membrane forms. The CLICs are expressed as soluble …

Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by
regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought …

Extant fold‐switching proteins remodel their secondary structures and change their functions
in response to environmental stimuli. These shapeshifting proteins regulate biological …