Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Developmental research has attempted to untangle the exact signals that control heart
growth and size, with knockout studies in mice identifying pivotal roles for Wnt and Hippo …

After myocardial infarction (MI), a significant portion of heart muscle is replaced with scar
tissue, progressively leading to heart failure. Human pluripotent stem cell‐derived …

Cardiovascular disease (CVD) has become a severe threat to human health, with morbidity
and mortality increasing yearly and gradually becoming younger. When the disease …

Human-based modelling and simulation offer an ideal testbed for novel medical therapies to
guide experimental and clinical studies. Myocardial infarction (MI) is a common cause of …

Cardiovascular diseases are the leading cause of death worldwide. Several strategies–
small molecules, gene therapy, surgeries, cardiac rehabilitation–have been developed to …

Engineered heart tissues (EHTs) built from human induced pluripotent stem cell-derived
cardiomyocytes (hiPSC-CMs) showed promising results for cardiac function restoration …

Cardiovascular diseases resulting from myocardial infarction (MI) remain a leading cause of
death worldwide, imposing a substantial burden on global health systems. Current MI …

Exercise-based cardiac rehabilitation participation is effective in improving cardiovascular
disease risk factor management, cardiopulmonary function, and quality of life. However, the …

Background Post myocardial infarction (MI) ventricles contain fibrotic tissue and may have
disrupted electrical properties, both of which predispose to an increased risk of life …