Consensus, debate, and prospective on pancreatic cancer treatments

J Wang, J Yang, A Narang, J He, C Wolfgang… - Journal of Hematology & …, 2024 - Springer
Pancreatic cancer remains one of the most aggressive solid tumors. As a systemic disease,
despite the improvement of multi-modality treatment strategies, the prognosis of pancreatic …

Intrafraction motion management with MR-guided radiation therapy

MF Fast, M Cao, P Parikh, JJ Sonke - Seminars in radiation oncology, 2024 - Elsevier
High quality radiation therapy requires highly accurate and precise dose delivery. MR-
guided radiotherapy (MRgRT), integrating an MRI scanner with a linear accelerator, offers …

[HTML][HTML] Gating and intrafraction drift correction on a 1.5 T MR-Linac: clinical dosimetric benefits for upper abdominal tumors

G Grimbergen, SL Hackett, F van Ommen… - Radiotherapy and …, 2023 - Elsevier
This work reports on the first seven patients treated with gating and baseline drift correction
on the high-field MR-Linac system. Dosimetric analysis showed that the active motion …

Stereotactic body radiotherapy with or without selective dismutase mimetic in pancreatic adenocarcinoma: An adaptive, randomised, double-blind, placebo-controlled …

CM Taniguchi, JM Frakes, TA Aguilera, M Palta… - The Lancet …, 2023 - thelancet.com
Background Stereotactic body radiotherapy (SBRT) has the potential to ablate localised
pancreatic ductal adenocarcinoma. Selective dismutase mimetics sensitise tumours while …

[HTML][HTML] Initial clinical experience building a dual CT-and MR-guided adaptive radiotherapy program

AT Price, JP Schiff, E Laugeman, B Maraghechi… - Clinical and …, 2023 - Elsevier
Introduction Our institution was the first in the world to clinically implement MR-guided
adaptive radiotherapy (MRgART) in 2014. In 2021, we installed a CT-guided adaptive …

[HTML][HTML] Stereotactic body radiotherapy for pancreatic cancer–A systematic review of prospective data

MA Shouman, F Fuchs, F Walter, S Corradini… - Clinical and translational …, 2024 - Elsevier
Purpose This systematic review aims to comprehensively summarize the current prospective
evidence regarding Stereotactic Body Radiotherapy (SBRT) in various clinical contexts for …

[HTML][HTML] Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer: A multi-center, open …

MD Chuong, P Lee, DA Low, J Kim, KE Mittauer… - Radiotherapy and …, 2024 - Elsevier
Background and purpose Radiation dose escalation may improve local control (LC) and
overall survival (OS) in select pancreatic ductal adenocarcinoma (PDAC) patients. We …

[HTML][HTML] Magnetic Resonance-Guided Cancer Therapy Radiomics and Machine Learning Models for Response Prediction

JA Fajemisin, G Gonzalez, SA Rosenberg, G Ullah… - Tomography, 2024 - mdpi.com
Magnetic resonance imaging (MRI) is known for its accurate soft tissue delineation of tumors
and normal tissues. This development has significantly impacted the imaging and treatment …

Efficacy of Neoadjuvant Radiotherapy After Chemotherapy and the Optimal Interval from Radiotherapy to Surgery for Borderline Resectable and Resectable …

WG Yun, YS Chae, Y Han, HS Jung, YJ Cho… - Annals of Surgical …, 2025 - Springer
Background Benefits of neoadjuvant treatment for pancreatic cancer with major vessel
invasion has been demonstrated through randomized controlled trials; however, the optimal …

[HTML][HTML] Online adaptive radiotherapy: Assessment of planning technique and its impact on longitudinal plan quality robustness in pancreatic cancer

KE Mittauer, S Yarlagadda, JM Bryant, N Bassiri… - Radiotherapy and …, 2023 - Elsevier
Abstract Background and Purpose Planning on a static dataset that reflects the simulation
day anatomy is routine for SBRT. We hypothesize the quality of on-table adaptive plans is …