Trastuzumab-containing therapy is a standard of care for patients with HER2+ breast cancer.
HER2 status is routinely assigned using in situ hybridization to assess HER2 gene …

Fluorescence in situ hybridization (FISH) is a standard technique used in routine diagnostics
of genetic aberrations. Thanks to simple FISH procedure is possible to recognize tumor …

Purpose.—To update key recommendations of the American Society of Clinical Oncology
(ASCO)/College of American Pathologists (CAP) human epidermal growth factor receptor 2 …

Currently, there is extensive information about circulating tumor cells (CTC) and their
prognostic value; however, little is known about other characteristics of these cells. In this …

Context.—In 2007 the American Society of Clinical Oncology/College of American
Pathologists made new recommendations for HER2 testing and redefined HER2 positivity …

Objectives Human epidermal growth factor receptor 2 (HER2) plays a central role as a
prognostic and predictive marker in breast cancer specimens. Reliable HER2 evaluation is …

Abstract The 2013 CAP/ASCO HER2 Testing Guidelines Update modified HER2 FISH
categories such that some cases with 'monosomy','co-amplification/polysomy', low-level …

Purpose The ratio of human epidermal growth factor receptor 2 (HER2) to CEP17 by
fluorescent in situ hybridization (FISH) with the centromeric probe CEP17 is used to …

Abstract Purpose of Review The human epidermal growth factor receptor 2 (HER2) is an
important prognostic and predictive biomarker in the breast cancer. The American Society of …

Apocrine carcinoma of the breast is a rare, special type of breast carcinoma showing distinct
morphologic, immunohistochemical and molecular genetic features. Apocrine epithelium …