Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key
clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host …

Osteoclasts are multinucleated cells with the unique ability to resorb bone matrix. Excessive
production or activation of osteoclasts leads to skeletal pathologies that affect a significant …

The stem cell niche is composed of a specialized population of cells that plays an essential
role in regulating adult stem cell self-renewal and differentiation. In adults, osteoblasts …

We previously reported a transgenic mouse model expressing herpesvirus thymidine kinase
(TK) gene under the control of a 2.3-kilobase fragment of the rat collagen α1 type I promoter …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Sex steroids are essential for skeletal development and the maintenance of bone health
throughout adult life, and estrogen deficiency at menopause is a major pathogenetic factor …

Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Previously, we discovered that periodontal ligament (PDL) cells not only support
osteoclastogenesis through cell‐to‐cell contact, but also inhibit the formation of tartrate …

Nowadays, there is an increased tendency for researches to focus on accelerating methods
for tooth movement due to the huge demand for adults for a shorter orthodontic treatment …