Triggering receptors expressed on myeloid cells (TREMs) encompass a family of cell-
surface receptors chiefly expressed by granulocytes, monocytes and tissue macrophages …

Metazoan tissue specification is associated with integration of macrophage lineage cells in
sub-tissular niches to promote tissue development and homeostasis. Oncogenic …

Bile acids (BAs) play a crucial role in nutrient absorption and act as key regulators of lipid
and glucose metabolism and immune homeostasis. Through the enterohepatic circulation …

Disordered lipid accumulation in the arterial wall is a hallmark of atherosclerosis. Previous
studies found that the expression of triggering receptor expressed on myeloid cells 2 …

Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor
protein predominantly expressed in microglia within the central nervous system (CNS) …

Acne is a common, chronic inflammatory condition affecting millions of people worldwide,
with significant negative impact on quality of life and mental health. Acne is characterized by …

Background: Cross-talk between sterol metabolism and inflammatory pathways has been
demonstrated to significantly affect the development of atherosclerosis. Cholesterol …

Spatial transcriptomics (ST) technologies have advanced to enable transcriptome-wide
gene expression analysis at submicron resolution over large areas. However, analysis of …

Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …

Sarcoidosis is a disease of unknown etiology in which granulomas form throughout the body
and is typically treated with glucocorticoids, but there are no approved steroid-sparing …