Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …

Arbutin is a compound of hydroquinone and D-glucose, and it has been over 30 years since
there have been serious studies on the skin lightening action of this substance. In the …

To fulfil the demands of rapid proliferation, tumour cells undergo significant metabolic
alterations. Suppression of hyperactivated metabolism has been proven to counteract …

The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …

Controlling unwanted hyperpigmentation is a major challenge in dermatology and
cosmetology, and safe and efficacious antimelanogenic agents are deemed useful for this …

Fluorescent probes have long been valuable tools in the study of biological systems. With
the ever-expanding range of known enzymatic biomarkers for disease, it has never been …

The tyrosinase enzyme, which is widely found in microorganisms, animals and plants, has a
significant position in melanogenesis, plays an important role in undesirable browning of …

Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …