Hepatocellular carcinoma (HCC) has become one of the major diseases that are threatening
human health in the 21st century. Currently there are many approaches to treat liver cancer …

Apoptosis is associated in many cases with the generation of reactive oxygen species (ROS)
in cells across a wide range of organisms including lower eukaryotes such as the yeast …

The accumulation of damaged and aggregated proteins is a hallmark of aging and
increased proteotoxic stress. To limit the toxicity of damaged and aggregated proteins and to …

During apoptosis, cells undergo characteristic morphological changes in which the
cytoskeleton plays an active role. The cytoskeleton rearrangements have been mainly …

The interaction of Candida albicans with macrophages is considered a crucial step in the
development of an adequate immune response in systemic candidiasis. An in vitro model of …

Transport defects may arise in various neurodegenerative diseases from failures in
molecular motors, microtubule abnormalities, and the chaperone/proteasomal degradation …

The worldwide occurrence of cyanobacterial blooms evokes profound concerns. The
presence of microcystins (MCs) in waters and aquatic food increases the risk to human …

The outbreak of cyanobacterial blooms induces the production and release of microcystins
(MCs) into water, representing a health hazard to aquatic organisms and even humans …

Background Alpha-tomatine (α-tomatine) is the major saponin in tomato (Lycopersicon
esculentum). This study investigates the chemopreventive potential of α-tomatine on …

Maslinic acid (MA) is an anti-tumoural agent which shows potent anti-proliferative properties
against the HT29 colon-cancer cells. To shed light upon the active mechanism of MA we …