The impact of oxidative stress and AKT pathway on cancer cell functions and its application to natural products

JP Shiau, YT Chuang, JY Tang, KH Yang, FR Chang… - Antioxidants, 2022 - mdpi.com
Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence

A Memarzia, S Saadat, F Asgharzadeh… - Journal of Cellular …, 2023 - Wiley Online Library
The most common type of cancer in the world is lung cancer. Traditional treatments have an
important role in cancer therapy. In the present review, the most recent findings on the …

Phytochemical screening and evaluation of antioxidant, anti-inflammatory, antimicrobial, and membrane-stabilizing activities of different fractional extracts of Grewia …

M Islam, AAS Prottay, I Sultana, A Al Faruq, MH Bappi… - Food Bioscience, 2023 - Elsevier
Abstract Background Grewia nervosa (Lour.) Panigrahi, a medicinal herb native to the steep
forested region of Bangladesh, is utilized as a treatment for a variety of diseases or …

Antiemetic effects of sclareol, possibly through 5-HT3 and D2 receptor interaction pathways: in-vivo and in-silico studies

MH Bappi, AAS Prottay, K Al-Khafaji, MS Akbor… - Food and Chemical …, 2023 - Elsevier
Background Emesis is a complex physiological phenomenon that serves as a defense
against numerous toxins, stressful situations, adverse medication responses, chemotherapy …

Multifaceted neuroprotective role of Punicalagin: a review

N Siddiqui, A Saifi, A Chaudhary, PN Tripathi… - Neurochemical …, 2024 - Springer
Millions of people worldwide are currently afflicted with neurologic conditions like a seizure,
depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease …

Global comparative transcriptomes uncover novel and population-specific gene expression in esophageal squamous cell carcinoma

A Alotaibi, VP Gadekar, PS Gundla, S Mandarthi… - Infectious Agents and …, 2023 - Springer
Background Esophageal squamous cell carcinoma (ESCC) has a poor prognosis and is one
of the deadliest gastrointestinal malignancies. Despite numerous transcriptomics studies to …

Exploring the anticancer potential and mechanisms of action of natural coumarins and isocoumarins

M Aqib, S Khatoon, M Ali, S Sajid, MA Assiri… - European Journal of …, 2024 - Elsevier
Natural coumarins and isocoumarins show significant therapeutic potential against cancer in
preclinical studies by targeting multiple pathways and processes. These compounds …

Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based …

Y Li, X Peng, G Wang, B Zan, Y Wang, J Zou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance In Traditional Chinese Medicine (TCM),
cholestasis liver disease belongs to jaundice. Yinchenzhufu decoction (YCZFD) is a classic …

Synthesis of Degradable Polyolefins Bearing Disulfide Units via Metathesis Copolymerization

Y **a, F Zhou, W Hao, S Tang - Polymers, 2023 - mdpi.com
Disulfide bonds are dynamic covalent bonds, which are easy to cleave and reform upon
chemical stimulus. Various methods including the oxidative coupling of thiols and …

Polyphenol-based targeted therapy for oral submucous fibrosis

CH Mehta, S Paliwal, MS Muttigi, RN Seetharam… - …, 2023 - Springer
Oral submucous fibrosis (OSF) is a chronic, progressive, and precancerous condition mainly
caused by chewing areca nut. Currently, OSF therapy includes intralesional injection of …