Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

MicroRNAs in stress signaling and human disease

JT Mendell, EN Olson - Cell, 2012 - cell.com
Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

E Van Rooij, EN Olson - Nature reviews Drug discovery, 2012 - nature.com
In recent years, prominent roles for microRNAs (miRNAs) have been uncovered in several
cardiovascular disorders. The ability to therapeutically manipulate miRNA expression and …

Consequences of oxidative stress in age-related macular degeneration

SG Jarrett, ME Boulton - Molecular aspects of medicine, 2012 - Elsevier
The retina resides in an environment that is primed for the generation of reactive oxygen
species (ROS) and resultant oxidative damage. The retina is one of the highest oxygen …

MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis

J Zhang, Y Xu, H Liu, Z Pan - Reproductive Biology and Endocrinology, 2019 - Springer
MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …

microRNAs in cardiovascular diseases: current knowledge and the road ahead

G Condorelli, MVG Latronico, E Cavarretta - Journal of the American …, 2014 - jacc.org
Over the last few years, the field of microribonucleic acid (miRNA) in cardiovascular biology
and disease has expanded at an incredible pace. miRNAs are themselves part of a larger …

From inflammation to current and alternative therapies involved in wound healing

MB Serra, WA Barroso, NN Silva… - International journal …, 2017 - Wiley Online Library
Wound healing is a complex event that develops in three overlap** phases: inflammatory,
proliferative, and remodeling. These phases are distinct in function and histological …

Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10

L Bao, BO You, SI Shi, Y Shan, Q Zhang, H Yue… - Oncogene, 2018 - nature.com
Benefiting from more precise imaging and radiotherapy, patients with locoregionally
nasopharyngeal carcinoma (NPC) have a significantly higher survival rate. Nonetheless …

MicroRNA-24 regulates vascularity after myocardial infarction

J Fiedler, V Jazbutyte, BC Kirchmaier, SK Gupta… - Circulation, 2011 - Am Heart Assoc
Background—Myocardial infarction leads to cardiac remodeling and development of heart
failure. Insufficient myocardial capillary density after myocardial infarction has been …

DNA methylation map of human atherosclerosis

S Zaina, H Heyn, FJ Carmona, N Varol… - Circulation …, 2014 - Am Heart Assoc
Background—Epigenetic alterations may contribute to the development of atherosclerosis.
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …