TGFβ signalling has key roles in cancer progression: most carcinoma cells have inactivated
their epithelial antiproliferative response and benefit from increased TGFβ expression and …

Endogenous stem cell homing refers to the transport of endogenous mesenchymal stem
cells (MSCs) to damaged tissue. The paradigm of using well-designed biomaterials to …

Collective metastasis is defined as the cohesive migration and metastasis of multicellular
tumor cell clusters. Disrupting various cell adhesion genes markedly reduces cluster …

Physical properties of tissue are increasingly recognised as major regulatory cues affecting
cell behaviours, particularly cell migration. While these properties of the extracellular matrix …

The metastatic process is arduous. Cancer cells must escape the confines of the primary
tumor, make their way into and travel through the circulation, then survive and proliferate in …

Pten is one of the most frequently mutated tumour suppressor gene in cancer. PTEN is
generally altered in invasive cancers such as glioblastomas, but its function in collective cell …

Cells migrate collectively through confined environments during development and cancer
metastasis. The nucleus, a stiff organelle, impedes single cells from squeezing into narrow …

Computational modeling of elasto-capillarity, ie, a fluid–structure interaction phenomenon
where the solid deformation is driven by capillary forces at fluid–fluid interfaces has recently …

Collective cell movements drive normal development and metastasis. Drosophila border
cells move as a cluster of 6–10 cells, where the role of the Rac GTPase in migration was first …

Current cell-based bone tissue regeneration strategies cannot cover large bone defects. K-
carrageenan is a highly hydrophilic and biocompatible seaweed-derived sulfated …