Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023‏ - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments

L Gatto, R Aebersold, J Cox, V Demichev, J Derks… - Nature …, 2023‏ - nature.com
Analyzing proteins from single cells by tandem mass spectrometry (MS) has recently
become technically feasible. While such analysis has the potential to accurately quantify …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024‏ - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Protein contaminants matter: building universal protein contaminant libraries for DDA and DIA proteomics

AM Frankenfield, J Ni, M Ahmed… - Journal of proteome …, 2022‏ - ACS Publications
Mass spectrometry-based proteomics is constantly challenged by the presence of
contaminant background signals. In particular, protein contaminants from reagents and …

Reporting guidelines to increase the reproducibility and comparability of research on microplastics

W Cowger, AM Booth, BM Hamilton… - Applied …, 2020‏ - journals.sagepub.com
The ubiquitous pollution of the environment with microplastics, a diverse suite of
contaminants, is of growing concern for science and currently receives considerable public …

Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019‏ - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical proteomics, 2023‏ - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Recommendations for reporting ion mobility Mass Spectrometry measurements

V Gabelica, AA Shvartsburg, C Afonso… - Mass spectrometry …, 2019‏ - Wiley Online Library
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

The death of the Job plot, transparency, open science and online tools, uncertainty estimation methods and other developments in supramolecular chemistry data …

DB Hibbert, P Thordarson - Chemical Communications, 2016‏ - pubs.rsc.org
Data analysis is central to understanding phenomena in host–guest chemistry. We describe
here recent developments in this field starting with the revelation that the popular Job plot …

A high-stringency blueprint of the human proteome

S Adhikari, EC Nice, EW Deutsch, L Lane… - Nature …, 2020‏ - nature.com
Abstract The Human Proteome Organization (HUPO) launched the Human Proteome Project
(HPP) in 2010, creating an international framework for global collaboration, data sharing …