Advances in the human skin microbiota and its roles in cutaneous diseases

Y Yang, L Qu, I Mijakovic, Y Wei - Microbial Cell Factories, 2022 - Springer
Skin is the largest organ in the human body, and the interplay between the environment
factors and human skin leads to some skin diseases, such as acne, psoriasis, and atopic …

Natural products in cosmetics

JK Liu - Natural products and bioprospecting, 2022 - Springer
The global cosmetics market reached US 500billionin2017andisexpectedtoexceedUS 800
billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as …

Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells

J Lee, WH Van Der Valk, SA Serdy, CC Deakin, J Kim… - Nature protocols, 2022 - nature.com
Human skin uses millions of hairs and glands distributed across the body surface to function
as an external barrier, thermoregulator and stimuli sensor. The large-scale generation of …

The PI3K-Akt-mTOR and associated signaling pathways as molecular drivers of immune-mediated inflammatory skin diseases: update on therapeutic strategy using …

T Roy, ST Boateng, MB Uddin, S Banang-Mbeumi… - Cells, 2023 - mdpi.com
The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

The use of micro-and nanocarriers for resveratrol delivery into and across the skin in different skin diseases—A literature review

B Szulc-Musioł, B Sarecka-Hujar - Pharmaceutics, 2021 - mdpi.com
In recent years, polyphenols have been extensively studied due to their antioxidant,
anticancer, and anti-inflammatory properties. It has been shown that anthocyanins …

Novel topical drug delivery systems in acne management: Molecular mechanisms and role of targeted delivery systems for better therapeutic outcomes

P Ghasemiyeh, S Mohammadi-Samani… - Journal of Drug Delivery …, 2022 - Elsevier
Acne vulgaris is a chronic inflammatory skin disorder that involves pilosebaceous units. Due
to the various harmful psychophysical consequences especially in teenagers and younger …

Exploitation of alternative skin models from academia to industry: Proposed functional categories to answer needs and regulation demands

M Portugal-Cohen, D Cohen, R Kohen… - Frontiers in Physiology, 2023 - frontiersin.org
The utilization of alternative skin models (ASM) for testing has sparked significant attention
in both academic and industrial environments. This aligns with the 3R principle, which …

Development of adapalene loaded liposome based gel for acne

A Arooj, AU Rehman, M Iqbal, I Naz, A Alhodaib… - Gels, 2023 - mdpi.com
Retinoids are considered the mainstay treatment for moderate to severe acne. Adapalene, a
third-generation retinoid, has physiochemical properties which hinder the effective delivery …

Electricity-producing Staphylococcus epidermidis counteracts Cutibacterium acnes

S Marito, S Keshari, S Traisaeng, DTT My… - Scientific reports, 2021 - nature.com
Staphylococcus epidermidis (S. epidermidis) ATCC 12228 was incubated with 2%
polyethylene glycol (PEG)-8 Laurate to yield electricity which was measured by a voltage …

Multi-omics analyses reveal bacteria and catalase associated with keloid disease

M Shan, M **ao, J Xu, W Sun, Z Wang, W Du, X Liu… - …, 2024 - thelancet.com
Background The pathology of keloid and especially the roles of bacteria on it were not well
understood. Methods In this study, multi-omics analyses including microbiome …