Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

The extracellular matrix (ECM) is dynamically tuned to optimize physiological function. Its
major properties, including composition and mechanics, profoundly influence cell biology …

Inflammation resolution is important for scar formation following myocardial infarction (MI)
and requires the coordinated actions of macrophages and fibroblasts. In this study, we …

Although aging is a known risk factor for idiopathic pulmonary fibrosis (IPF), the pathogenic
mechanisms that underlie the effects of advancing age remain largely unexplained. Some …

Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disorder with increasing incidence.
Mitochondrial oxidative stress in alveolar macrophages is directly linked to pulmonary …

Pathological remodeling of the extracellular matrix (ECM) by fibroblasts leads to organ
failure. Development of idiopathic pulmonary fibrosis (IPF) is characterized by a progressive …

Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Pulmonary fibrosis occurs in a variety of clinical settings, constitutes a major cause of
morbidity and mortality, and represents an enormous unmet medical need. However, the …

Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …