Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system that are
capable of killing virally infected and/or cancerous cells. Nearly 20 years ago, NK cell …

Immunotherapy, with an increasing number of therapeutic dimensions, is becoming an
important mode of treatment for cancer patients. The inhibition of immune checkpoints …

NK cells play important roles in innate defenses against viruses and in the control of tumor
growth and metastasis. The regulation/induction of NK cell function is mediated by an array …

NK cells are cytotoxic components of innate lymphoid cells (ILC) that provide a first line of
defense against viral infections and contribute to control tumor growth and metastasis. Their …

Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …

Purpose This multinational study evaluated the antitumor activity of nivolumab in
nasopharyngeal carcinoma (NPC). Tumor and plasma-based biomarkers were investigated …

Antibodies targeting immune checkpoints are emerging as potent and viable cancer
therapies, but not all patients respond to these as single agents. Concurrently targeting …

Simple Summary Chemoimmunotherapy is an emerging treatment option for cancer that
combines traditional chemotherapy with immunotherapy. This approach aims to increase the …

Polymorphic HLAs form the primary immune barrier to cell therapy. In addition, innate
immune surveillance impacts cell engraftment, yet a strategy to control both, adaptive and …