Fucoidan structure and activity in relation to anti-cancer mechanisms
Fucoidan is a natural derived compound found in different species of brown algae and in
some animals, that has gained attention for its anticancer properties. However, the exact …
some animals, that has gained attention for its anticancer properties. However, the exact …
[HTML][HTML] JNK-signaling: A multiplexing hub in programmed cell death
Jun N-terminal kinases or JNKs have been shown to be involved in a wide array of signaling
events underlying tumorigenesis and tumor progression. Through its interaction with a …
events underlying tumorigenesis and tumor progression. Through its interaction with a …
Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway
X Cao, M Fu, R Bi, X Zheng, B Fu, S Tian, C Liu, Q Li… - Chemosphere, 2021 - Elsevier
Cadmium, a heavy metal pollutant in industrial production, is found in air, water and soil,
which is harmful to human health and can lead to diseases, such as asthma, lung cancer …
which is harmful to human health and can lead to diseases, such as asthma, lung cancer …
A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via synergistic ROS augment and autophagy blockage
Y Zhang, J Zhao, L Zhang, Y Zhao, Y Zhang, L Cheng… - Nano Today, 2023 - Elsevier
The ultrasound-triggered sonodynamic therapy (SDT) with high tissue penetration, high
spatiotemporal selectivity, and non-invasive advantages represents an emerging approach …
spatiotemporal selectivity, and non-invasive advantages represents an emerging approach …
Formononetin: a review of its anticancer potentials and mechanisms
Cancer, a complex yet common disease, is caused by uncontrolled cell division and
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …
Molecular mechanisms for tumour resistance to chemotherapy
ST Pan, ZL Li, ZX He, JX Qiu… - Clinical and Experimental …, 2016 - Wiley Online Library
Chemotherapy is one of the prevailing methods used to treat malignant tumours, but the
outcome and prognosis of tumour patients are not optimistic. Cancer cells gradually …
outcome and prognosis of tumour patients are not optimistic. Cancer cells gradually …
Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway …
HW Zhang, JJ Hu, RQ Fu, X Liu, YH Zhang, J Li, L Liu… - Scientific reports, 2018 - nature.com
Anticancer activities of flavonoids derived from Tephroseris kirilowii (Turcz.) Holub. were
evaluated in human cancer cells. We isolated and identified, for the first time, eight …
evaluated in human cancer cells. We isolated and identified, for the first time, eight …
[HTML][HTML] Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
D Li, W Ren, Z Jiang, L Zhu - Molecular medicine …, 2018 - spandidos-publications.com
Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) is characterized by
uncontrolled progressive lung inflammation. Macrophages serve a key role in the …
uncontrolled progressive lung inflammation. Macrophages serve a key role in the …
Autophagy: a key regulator of homeostasis and disease: an overview of molecular mechanisms and modulators
L Gómez-Virgilio, MC Silva-Lucero, DS Flores-Morelos… - Cells, 2022 - mdpi.com
Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …
cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works …
Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies
MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …
biological progression involving various genetic, environmental, and lifestyle factors. The …