Urea-aromatic interactions in biology

S Raghunathan, T Jaganade, UD Priyakumar - Biophysical Reviews, 2020‏ - Springer
Noncovalent interactions are key determinants in both chemical and biological processes.
Among such processes, the hydrophobic interactions play an eminent role in folding of …

Transmembrane proteins—Different anchoring systems

I Roterman, K Stapor… - … : Structure, Function, and …, 2024‏ - Wiley Online Library
Transmembrane proteins are active in amphipathic environments. To stabilize the protein in
such surrounding the exposure of hydrophobic residues on the protein surface is required …

SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity

S Hartmann, L Radochonski, C Ye… - Research …, 2024‏ - pmc.ncbi.nlm.nih.gov
SARS-CoV-2 uses the double-membrane vesicles as replication organelles. However, how
virion assembly occurs has not been fully understood. Here we identified a SARS-CoV-2 …

Cooperation of hydrophobic gating, knock-on effect, and ion binding determines ion selectivity in the p7 channel

S Padhi, UD Priyakumar - The Journal of Physical Chemistry B, 2016‏ - ACS Publications
Ion channels selectively allow certain ions to pass through at much higher rates than others,
and thereby modulate ionic concentrations across cell membranes. The current molecular …

pH-mediated gating and formate transport mechanism in the Escherichia coli formate channel

S Padhi, LK Reddy, UD Priyakumar - Molecular Simulation, 2017‏ - Taylor & Francis
Formate channels play a crucial role in the metabolism of several different kinds of bacteria
by bringing about uptake and export of formate ions. The current study investigates the …

[PDF][PDF] Modeling Structures and Transport Phenomena of Transmembrane Channels and Transporters

S Padhi - 2016‏ - cdn.iiit.ac.in
Membrane proteins account for more than half of present day drug targets, but an
understanding of structure-function relationships in these proteins continues to be a …