Zebrafish as a successful animal model for screening toxicity of medicinal plants

A Modarresi Chahardehi, H Arsad, V Lim - Plants, 2020‏ - mdpi.com
The zebrafish (Danio rerio) is used as an embryonic and larval model to perform in vitro
experiments and developmental toxicity studies. Zebrafish may be used to determine the …

[HTML][HTML] Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans

WY Ong, DR Herr, GY Sun, TN Lin - Molecules, 2022‏ - mdpi.com
Recent studies on the ethnomedicinal use of Clinacanthus nutans suggest promising anti-
inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the leaves …

Alternative model organisms for toxicological fingerprinting of relevant parameters in food and nutrition

G Sandner, A König, M Wallner… - Critical reviews in food …, 2022‏ - Taylor & Francis
In the field of (food) toxicology, there is a strong trend of replacing animal trials with
alternative methods for the assessment of adverse health effects in humans. The …

Quantification and assessment of chemical footprint of VOCs in polyester fabric production

W Qian, Y Guo, X Wang, X Qiu, X Ji, L Wang… - Journal of Cleaner …, 2022‏ - Elsevier
Volatile organic compounds (VOCs) can easily diffuse into atmosphere, causing deleterious
effects on human health via different exposure pathways due to their high volatility and …

[HTML][HTML] Subacute Oral Administration of Clinacanthus nutans Ethanolic Leaf Extract Induced Liver and Kidney Toxicities in ICR Mice

A Aliyu, MR Shaari, NS Ahmad Sayuti, MFH Reduan… - Molecules, 2020‏ - mdpi.com
This study investigated the leaves of Clinacanthus nutans for its bioactive compounds and
acute and subacute toxicity effects of C. nutans ethanolic leaf extract (CELE) on blood, liver …

Phytochemical and Safety Evaluations of Zingiber ottensii Valeton Essential Oil in Zebrafish Embryos and Rats

W Thitinarongwate, R Mektrirat, W Nimlamool… - Toxics, 2021‏ - mdpi.com
Zingiber ottensii Valeton (ZO) exhibits pharmacological activity and has long been used in
traditional medicine. However, reports about its safety profiles are limited. The present study …

The psychoactive effects of Bryophyllum pinnatum (Lam.) Oken leaves in young zebrafish

K Martins Fernandes Pereira… - PLoS …, 2022‏ - journals.plos.org
Bryophyllum pinnatum (Lam.) Oken (BP) is a plant that is used worldwide to treat
inflammation, infections, anxiety, restlessness, and sleep disorders. While it is known that BP …

Preliminary Phytochemical Screening, In Vitro Antidiabetic, Antioxidant Activities, and Toxicity of Leaf Extracts of Psychotria malayana Jack

TS Nipun, A Khatib, QU Ahmed, MHM Nasir, F Supandi… - Plants, 2021‏ - mdpi.com
Psychotria malayana Jack belongs to the Rubiacea and is widespread in Southeast Asian
countries. It is traditionally used to treat diabetes. Despite its potential medicinal use …

The Reproductive Toxicity Associated with Dodonaea viscosa, a Folk Medicinal Plant in Saudi Arabia

MF Khan, AS Alqahtani, OM Almarfadi… - Evidence‐Based …, 2021‏ - Wiley Online Library
Dodonaea viscosa is a medicinal plant which is being used to treat various diseases in
humans. The available safety data suggest that the plant does not produce any side effects …

Toxicity evaluation of traditional and organic yerba mate (Ilex paraguariensis A. St.-Hil.) extracts

LC Abrão, DG Costa-Silva, MG Santos… - Journal of Toxicology …, 2022‏ - Taylor & Francis
Yerba mate (Ilex paraguariensis A. St.-Hil.) is an important source of biologically active
compounds with pharmacological potential. The aim of this study was to examine the toxicity …