Prevention of Central Line–Associated Bloodstream Infections | New England Journal of Medicine
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Healthcare-associated infections (HCAIs) are a major source of morbidity and mortality and
are the second most prevalent cause of death. Furthermore, it has been reported that for …

Background Adverse events during hospitalization are a major cause of patient harm, as
documented in the 1991 Harvard Medical Practice Study. Patient safety has changed …

Acute-on-chronic liver failure (ACLF), which was described relatively recently (2013), is a
severe form of acutely decompensated cirrhosis characterised by the existence of organ …

Introduction: Staphylococcus aureus is one of the most common pathogens in health care
facilities and in the community, and can cause invasive infections, sepsis, and death …

Objective: Decades-old, common ICU practices including deep sedation, immobilization,
and limited family access are being challenged. We endeavoured to evaluate the …

Background Multidrug-resistant (MDR) bacteria that are commonly associated with health
care cause a substantial health burden. Updated national estimates for this group of …

The Institute of Medicine's To Err Is Human, published in 1999, represented a watershed
moment for the US health care system. The report dramatically raised the profile of patient …

Background: The coronavirus disease 2019 (COVID-19) pandemic has had a considerable
impact on US hospitalizations, affecting processes and patient population. Objective: To …

Evidence-based guidelines for implementation and measurement of antibiotic stewardship
interventions in inpatient populations including long-term care were prepared by a …